The impact of alcohol on mental health is often underestimated, despite its widespread use in society. In a recent episode of Southwest General Health Talk, psychiatrist Dr. Muhammad A. Sofab discusses how alcohol affects brain chemistry, mood, and overall mental well-being. While alcohol initially produces a calming effect by increasing GABA and dopamine neurotransmission, it also suppresses glutamate activity, leading to memory impairment, speech difficulties, and coordination issues. Over time, frequent alcohol use disrupts the brain’s natural balance, increasing the risk of anxiety, depression, and other mental health challenges.

Dr. Sofab highlights the dangers of using alcohol to self-medicate stress or emotional distress, a practice commonly portrayed in media and social settings. He warns that alcohol’s sedative effects can interfere with psychiatric medications, reducing their effectiveness and increasing risks such as drowsiness, memory problems, and even dementia, particularly in older adults. He explains that alcohol and mental health conditions have a bidirectional relationship, where heavy drinking can both stem from and contribute to depression and anxiety. In severe cases, long-term alcohol use alters brain function, making it harder for individuals to experience pleasure and leading to persistent low mood.

For those concerned about their own or a loved one’s drinking habits, Dr. Sofab suggests looking for warning signs such as increased irritability, difficulty managing stress without alcohol, blackouts, or withdrawal symptoms. He emphasizes that moderation is key but notes that the safest option, especially for those with existing mental health conditions, is to avoid alcohol entirely. Southwest General Health Center offers a range of resources, from primary care screenings to intensive addiction recovery programs, to help individuals manage alcohol-related mental health concerns and find healthier coping strategies.

Find more from Southwest General Health Talk Podcasts (USA, March 2025)